What is Homology?
In biology, Homology is the similarity of structure, physiology, or development of different species of organisms based on their decent from a common ancestor. [1] These similarities haveled to a deeper understanding of evolution [2] and continue to aid in groundbreaking research in areas related to disease and discovery of new drugs. [3] In this case, we will be looking at the homology of the genetic sequence of the ARNT gene across a few of the model organisms.
Homo Sapiens (Human)
ARNT
Accession Number: NP_001184254.1
Length: 773 a.a.
Identity: 100%
Caenorhabditis Elegans (Roundworm)
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Danio Rerio (Zebrafish)
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Drosophila Melanogaster (Housefly)
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Mus Musculus (Mouse)
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Protein Homologs
arnt.jcn.txt | |
File Size: | 3 kb |
File Type: | txt |
Discussion
This data shows that there are homologs for the human ARNT gene present in many of the model organisms with mus musculus having the highest percent homology. Any of these model organisms could be used in research and be useful for further phylogenetic and domain analyses.
References
[1] Homology. (n.d.). Retrieved from https://bachinskigen564s19.weebly.com/homology.html
[2] (n.d.). Retrieved from https://evolution.berkeley.edu/evolibrary/article/_0_0/evo_09
[3] Muhammed, M. T., & Aki‐Yalcin, E. (2018, October 8). Homology modeling in drug discovery: Overview, current applications, and future perspectives. Retrieved from https://onlinelibrary.wiley.com/doi/full/10.1111/cbdd.13388
Header Image: https://psmag.com/environment/why-your-race-isnt-genetic-82475
All other images are linked
[2] (n.d.). Retrieved from https://evolution.berkeley.edu/evolibrary/article/_0_0/evo_09
[3] Muhammed, M. T., & Aki‐Yalcin, E. (2018, October 8). Homology modeling in drug discovery: Overview, current applications, and future perspectives. Retrieved from https://onlinelibrary.wiley.com/doi/full/10.1111/cbdd.13388
Header Image: https://psmag.com/environment/why-your-race-isnt-genetic-82475
All other images are linked